Three years into his pancreatic cancer diagnosis, the New York pastor will undergo immunotherapy again.

Tim Keller shared on Sunday that he will once again go through a “brutal” treatment for his pancreatic cancer and asked for prayers.

Last June, Keller participated in an inpatient immunotherapy trial at the National Institutes of Health’s National Cancer Institute, which he said had “shown great promise in potentially curing cancer.” The 72-year-old is returning to the Bethesda, Maryland, facility next month to do another variation of that immunotherapy on new tumors.

The tumors “are unfortunately in some fairly inconvenient places,” Keller said, “so the doctors encouraged us to go through the treatment again, this time targeting a different genetic marker of the cancer.”

“It was brutal last June, so we approach this with an awareness of how much prayer we need,” Keller wrote on Twitter. “Please pray for our trust and dependence on God, for his providential oversight of the medical preparations now in process, and for our desire to glorify God in whatever comes our way. Thank You.”

The longtime pastor of Redeemer Presbyterian Church in Manhattan, Keller was diagnosed with stage IV pancreatic cancer in May 2020. He went through 14 rounds of chemotherapy, followed by a surgery to remove nodules the following year.

In June 2022, he first went through the month-long immunotherapy treatment at the National Cancer Institute. At the time, his son Michael Keller posted an update saying, “Things were scary for a bit but God was gracious, working through your prayers and the skill of the doctors, and now he is doing much better.”

Last July, Keller reported that the initial signs from the immunotherapy were encouraging. Eight months later, he said it …

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